Severe Asthma

ERS has now resumed sales of printed books worldwide, with the exception of a small number of countries (https://www.ersbookshop.com/shipping-in-2020-4-w.asp). Electronic versions of many ERS books are available from our dedicated website at https://books.ersjournals.com/, or from Google Play Books, ebooks.com and the Amazon Kindle Store (in some territories), as well as from many library ebook vendors. For more information visit: https://books.ersjournals.com/ebooks-availability

Edited by Kian Fan Chung, Elliot Israel and Peter G. Gibson
Severe asthma is a form of asthma that responds poorly to currently available medication, and its patients represent those with greatest unmet needs. In the last 10 years, substantial progress has been made in terms of understanding some of the mechanisms that drive severe asthma; there have also been concomitant advances in the recognition of specific molecular phenotypes. This ERS Monograph covers all aspects of severe asthma epidemiology, diagnosis, mechanisms, treatment and management  but has a particular focus on recent understanding of mechanistic heterogeneity based on an analytic approach using various 'omics platforms applied to clinically well-defined asthma cohorts. How these advances have led to improved management targets is also emphasised. This book brings together the clinical and scientific expertise of those from around the world who are collaborating to solve the problem of severe asthma.

This book contains a unique code that gives you free access to the eBook. If you would like to buy the eBook only and not receive a print copy, visit books.ersjournals.com

Contents list 
1. Definition and impact 
2. Understanding the experience of people living with severe asthma
3. The contribution of comorbidities, psychosocial factors and adherence to the presentation of severe asthma
4. Clinical phenotypes: adults
5. Clinical phenotypes: children
6. Mechanisms underlying fixed airflow obstruction and exacerbations
7. Clinical biomarkers and noninvasive assessment 
8. Imaging 
9. Pathophysiology 
10. The lessons from U-BIOPRED 
11. SARP: dissecting subphenotypes and endotypes
12. Molecular phenotypes
13. Metabolic dysfunction 
14. Corticosteroid responsiveness and resistance 
15. Mechanisms in children
16. Evaluation and management in children
17. Evaluation of difficult-to-treat and severe asthma in adults
18. Biologics targeting type 2 inflammation
19. Nonpharmacological interventions: behavioural and interventional approaches
20. Management in adults
21. The next decade of continuing progress

This book also includes clinical cases

ISBN 978-1-84984-103-0