Asthma

Edited by David J. Jackson, Vanessa M. McDonald and Ian D. Pavord
Asthma is one of the most prevalent respiratory diseases, affecting ~8% of the world's population. Given the huge impact of the condition, and the vast amount of progress that has been made in the field in the last 10 years, a Monograph on the topic is now timely. Opening with a section on pathophysiology, then moving on to cover diagnosis and assessment, therapeutic approaches, comorbidities and special circumstances, this Monograph provides an up-to-date overview of the current understanding of asthma mechanisms and how to deliver care for people with asthma.

Contents list 

Pathophysiology
1. Innate and adaptive immune responses in asthma
2. Airway hyperreponsiveness
3. Airway remodelling and small airways dysfunction in asthma
4. Mucus plugging in severe asthma
5. Mechanisms of asthma exacerbations
6. The airway microbiome in asthma
7. The impact of air pollution in asthma

Diagnosis and assessment
8. Diagnosis of asthma in adults
9. Diagnosing asthma in children
10. Type 2 biomarkers and assessment of risk
11. Differentiating difficult from severe asthma
12. Assessment of medication adherence
13. Learnings from asthma fatalities
14. CT and MRI of asthma
15. Digital health for asthma

Therapeutic approaches
16. Biomarker-guided versus symptom-guided therapy
17. Anti-inflammatory reliever therapy
18. Biologic therapies in asthma
19. Options in the absence of type 2 inflammation
20. Allergen immunotherapy in asthma
21. Oral corticosteroid stewardship in asthma

Comorbidities
22. Chronic rhinosinusitis with nasal polyposis and nonsteroidal anti-inflammatory drug-exacerbated respiratory disease
23. Obesity
24. COPD as a comorbidity of asthma
25. Allergic bronchopulmonary aspergillosis
26. Eosinophilic granulomatosis with polyangiitis
27. Inducible laryngeal obstruction
28. Breathing pattern disorder
29. Psychological and behavioural disorders

Special circumstances
30. Asthma in pregnancy
31. Work-related asthma

Print ISBN: 978-1-84984-190-0
eISBN: 978-1-84984-191-7
EPUB ISBN: 978-1-84984-192-4