Edited by Aurelie Fabre, John R. Hurst and Sheila Ramjug
The story of COVID-19 now seems so familiar: from the first reported case of a new respiratory infection in China in December 2019, to a pandemic that rapidly changed the world. Respiratory clinicians and scientists were at the forefront of delivering healthcare for people with COVID-19, leading efforts to understand this novel virus and disease, developing and testing strategies to better prevent and treat it. These endeavours extended not only to the acute illness, but also to understanding the longer-term consequences. The pace of knowledge acquisition was rapid but is now maturing. This Monograph therefore provides a timely and valuable state-of-the-art summary for clinicians and scientists on our understanding of this virus and its consequences to date. It is essential reading for all those involved in the care of people who are or who have been affected by COVID-19.
1. Respiratory failure: a patient's perspective and clinical cases
2. Epidemiology: global spread, risk factors for disease incidence, severity and mortality
3. Historical perspective: other human coronavirus infectious diseases, SARS and MERS
4. Drug repurposing and other strategies for rapid antiviral development: lessons from the early stage of the pandemic
5. Can the immune system be targeted to treat COVID-19?
6. Lung pathology
7. Clinical features and acute management in adults
8. Management in the ICU
9. Clinical features and acute management in children
11. Post-COVID-19 sequelae
12. Post-COVID-19 rehabilitation
13. Clinical trials during the pandemic: research design and lessons
14. Economic, physical and social determinants of health during lockdown: a call for renewed societal responses
15. Vaccines: immunology regulation and clinical management